Fibrinogen β–derived Bβ15-42 peptide protects against kidney ischemia/ reperfusion injury
نویسندگان
چکیده
منابع مشابه
THROMBOSIS AND HEMOSTASIS Fibrinogen –derived B 15-42 peptide protects against kidney ischemia/ reperfusion injury
1Renal Division, Department of Medicine, Brigham and Women’s Hospital and 2Center for Biomedical Informatics, Harvard Medical School, Boston, MA; 3Departamento de Nefrología y Metabolismo Mineral, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zúbiran, Mexico City, Mexico; 4Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México and Instituto Nacional de Ci...
متن کاملFibrinogen β-derived Bβ(15-42) peptide protects against kidney ischemia/reperfusion injury.
Ischemia/reperfusion (I/R) injury in the kidney is a major cause of acute kidney injury (AKI) in humans and is associated with significantly high mortality. To identify genes that modulate kidney injury and repair, we conducted genome-wide expression analysis in the rat kidneys after I/R and found that the mRNA levels of fibrinogen (Fg)α, Fgβ, and Fgγ chains significantly increase in the kidney...
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ژورنال
عنوان ژورنال: Blood
سال: 2011
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2011-02-338061